Highway 21 Seafood
About This Spot
Stepping into Highway 21 Seafood feels a bit like uncovering a well-kept local secret along Beaufort’s welcoming Trask Parkway. The pace here is unhurried, inviting you to take a moment away from the day’s rush and breathe in the clean, salty air that seems to carry the ocean right inside. It’s a place where the hum of friendly conversation blends effortlessly with the gentle coolness of freshly caught seafood on ice, creating a quietly vibrant atmosphere grounded in care and community.
Behind the counters, you’ll find people who genuinely know their craft and appreciate the rhythms of the coastal waters—from the busy hands sorting through South Carolina shrimp to the patient smiles ready to guide you toward the day’s freshest catch. There’s an easy openness here, the kind that makes you feel comfortable to ask questions, learn a little, and maybe even share a story or two. It’s this human touch that transforms a simple seafood market into a space full of subtle connections and discovery.
As you move through the market, what stands out is more than just the abundance of options; it’s the consistent freshness paired with thoughtful care. The selection draws you in—crabs brought in at their prime, shrimp that taste like the coast itself, and fish so carefully handled you can sense each one’s journey from the water to your hands. The prices reflect a respect for local sourcing and community, making it a place where both locals and visitors feel equally welcome to explore new flavors or stick to familiar favorites.
Highway 21 Seafood carries that comforting balance of tradition and everyday discovery. It’s a place where the spotlight isn’t just on what’s for sale, but on the small human moments between buyer and seller—moments that gently remind you why local markets remain the heartbeats of their communities.
What’s Available Here
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Small Business
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Delivery
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Wheelchair-accessible car park
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Wheelchair-accessible entrance
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Credit cards
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Debit cards
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NFC mobile payments
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SNAP/EBT
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Credit cards
Location & Hours
| Monday | 10:00 AM - 06:00 PM | |
| Tuesday | 10:00 AM - 06:00 PM | |
| Wednesday | 10:00 AM - 06:00 PM | |
| Thursday | 10:00 AM - 06:00 PM | |
|---|---|---|
| Friday | 10:00 AM - 06:00 PM | |
| Saturday | 10:00 AM - 06:00 PM | |
| Sunday | 10:00 AM - 05:00 PM |
Shane Miller 04 Jan 2026
Great prices. Super fresh seafood. Friendly staff as well.
Nancy Lunden 17 Dec 2025
I was greeted and waited on by a a friendly young man . Everything I bought has been truly fresh and just absolutely delish . The market has our SC shrimp! Excellent variety and always fresh
Wendy Jackson 04 Nov 2025
Great shrimp at a great price! Friendly folks as well. They have lots of other things we look forward to trying now that we have discovered Highway 21!
Andrew Broussard 03 Nov 2025
Good service got a dozen of blue crabs and they were All Rusty's meaning they were good clerk told me when he brought my order to me fast and friendly
Bryan 28 Oct 2025
The freshness and selection here are crazy. I don’t know where all this comes from and I’m surprised how big their list is for fresh fish. Prices are great too
Brandy H 24 Oct 2025
This place has a great selection is very fresh sea food! Bought a couple bags of fresh scallops. Price was reasonable, they seared nice and they were absolutely amazing! I'll definitely be back if I'm in the area. Thanks for the great service and great scallops!
Deborah newman 23 Oct 2025
Highway 21 Seafood is AMAZING! The people are so nice and helpful. The seafood is delicious with lots to choose from. The prices are reasonable and a good value.